International Journal of Pharmaceutical Sciences and Drug Analysis
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P-ISSN: 2788-9246, E-ISSN: 2788-9254
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International Journal of Pharmaceutical Sciences and Drug Analysis

2021, Vol. 1, Issue 1, Part A

Phytochemical and biological activities of Khat (Catha edulis Forsk): A review


Author(s): Khaled Rashed

Abstract: Catha edulis Forsk (Celastraceae)], is an ancient plant associated with psychological, health and socioeconomic issues on humans. Khat (the flower of paradise) is a plant vastly used on the African continent. Many different compounds are found in khat including alkaloids, terpenoids, flavonoids, sterols, glycosides, tannins, amino acids, vitamins and minerals. The phenylalkylamines and the cathedulins are the major alkaloids which are structurally related to amphetamine. The major effects of khat include those on the gastro-intestinal system and on the nervous system. Constipation, urine retention and acute cardiovascular effects may be regarded as autonomic (peripheral) nervous system effects; increased alertness, dependence, tolerance and psychiatric symptoms as effects on the central nervous system. The main toxic effects include increased blood pressure, tachycardia, insomnia, anorexia, constipation, general malaise, irritability, migraine and impaired sexual potency in men.

Pages: 32-34 | Views: 409 | Downloads: 233

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How to cite this article:
Khaled Rashed. Phytochemical and biological activities of Khat (Catha edulis Forsk): A review. Int J Pharm Sci Drug Anal 2021;1(1):32-34.
International Journal of Pharmaceutical Sciences and Drug Analysis