Author(s): Gudisa Bereda

Abstract: Amlodipine’s function in alleviating stable angina is owing to the decreasing of afterload secondary to its vasodilatory and antihypertensive properties. Amlodipine suppresses calcium ion influx across cell membranes selectively, with a higher outcome on vascular smooth muscle cells than on cardiac muscle cells. Amlodipine tablets are indicated for the symptomatic treatment of chronic stable angina. They perhaps used alone or in combination with distinctive antianginal agents. Amlodipine is initially administered orally and is available as 2.5 mg, 5 mg, and 10 mg tablets. The eloquent adverse effects of amlodipine involve peripheral edema (swelling of your legs or ankles), heart failure, hypoesthesia, neuropathy peripheral, paresthesia. Amlodipine tablets should be taken with a glass of liquid (e.g. a glass of water) with or without food. Grapefruit juice and grapefruit should not be consumed by people who are taking Amlodipine tablets.

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