Author(s): Niraj T Katare, Ajay G Mohite, Vaibhav P, Uplanchiwar, Krutika S Bobde and Vaishnavi B Pawar

Abstract: Gene therapy requires introduction of new genetic material into the tissue or cell to transform gene expression or alter the properties of cell for therapeutic purposes. Consequently, there is a need for the development of the safe and efficacious strategies like gene therapy to improve the survival rate and anticipation of life for cancer patients. The motto of gene therapy is to transfer a curative gene into the host cell to shown its remedial effect. The choice of delivery vehicle relies on the desired individuality of the gene therapy. The starting gene therapy trials used remedial genes driven by viral promoters like the CVM promoter, which effects peculiar toxicity in both normal cell and tissue, as well cancer cell to overcome this limitation, tumour specific promoter methods have been created to attack target cancer cells effectively. Gene therapy has the potential to revolutionize cancer treatment.

DOI: 10.22271/27889246.2023.v3.i1b.55

Pages: 109-118 | Views: 483 | Downloads: 216

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