Author(s): Vimal Kishore, Sunena and Pawan Jalwal

Abstract: Both the number of fungi that cause systemic diseases and the number of those diseases itself are on the rise. Antifungal agents that are used to treat include the azole group of medications (Ketoconazole, Fluconazole, and Itraconazole), Nystatin, polyene antibiotics (Amphotericin B), and fluoropyrimidines (Flu Cytosine). Innovative drug delivery strategies for topical antifungal treatment, determined by the kind of formulations are categorized as mucoadhesive gels, mucoadhesive emulsions, liposomes, nanospheres and nanoparticles-based systems etc. A new era in the management of fungal infections has been brought about by the development of lipid-based antifungal drugs. Hopefully, developments in liposome technology will lead to antifungal regimens that are less hazardous and more effective. Novel drug delivery systems for antifungal therapy, aiming at reducing the side effects and maximizing the antifungal activity have added a new dimension to the treatment of fungal infections. New Comparing drug delivery systems for antifungal therapy to their parent compounds administered by conventional systems, the former exhibits greater antifungal activity and less toxic effects.

Pages: 46-49 | Views: 480 | Downloads: 226

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