International Journal of Pharmaceutical Sciences and Drug Analysis
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P-ISSN: 2788-9246, E-ISSN: 2788-9254
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2024, Vol. 4, Issue 1, Part B

Comparison of potentiometric, pH, and indicator titration methods for the detection of ibuprofen in tablets and suspensions


Author(s): Mohammed Al-Tawil

Abstract: Ibuprofen has anti-inflammatory effects. It is a weak monobasic organic acid. It is insoluble in water but can be dissolved in organic solvents such as methanol and ethanol. This research aimed to determine the ibuprofen content in two pharmaceutical forms using potentiometric, pH, and indicator titration methods: compressed tablets and suspensions. Ibuprofen tablets and suspensions were purchased from various pharmacies in Ibb, Yemen. The titrations were conducted using a sodium hydroxide solution as the titrant. The three methods had no significant differences, but the potentiometric and pH methods were the most effective for estimating ibuprofen in colored suspensions. Additionally, the study revealed no significant difference between the measured ibuprofen content and the amount stated on the product label in Ibb city, Yemen.

Pages: 144-153 | Views: 171 | Downloads: 97

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International Journal of Pharmaceutical Sciences and Drug Analysis
How to cite this article:
Mohammed Al-Tawil. Comparison of potentiometric, pH, and indicator titration methods for the detection of ibuprofen in tablets and suspensions. Int J Pharm Sci Drug Anal 2024;4(1):144-153.
International Journal of Pharmaceutical Sciences and Drug Analysis
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