Synthesis and evaluation of oxadiazole derivatives in drug design and development
Author(s): Sarada Prasad Sarangi and K Saravanan
Abstract: The current review summarizes synthesis and biological activity of the oxadiazole derivatives to date. The results described in the review are of high significance and priority for the development of new approaches in the drug design and discovery. Numerous advances have been achieved in the synthetic methodologies during the last years, which allowed obtaining a number of novel and diverse structural scaffolds. This has dramatically expanded the functionalization and derivatization potential of these heterocyclic compounds and translated them from a kind of laboratory product into an important part of the therapeutically valuable molecules. The review summarizes succintly information on newly emerging and traditional approach for development of small oxadiazoles and their biological activity and illustrates the impact of the oxadiazoles derivatives on human pharmaceutical development.
Sarada Prasad Sarangi, K Saravanan. Synthesis and evaluation of oxadiazole derivatives in drug design and development. Int J Pharm Sci Drug Anal 2026;6(1):01-06. DOI: 10.22271/27889246.2026.v6.i1a.148